The use of metformin is associated with decreased lumbar radiculopathy pain [Erratum]
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منابع مشابه
The use of metformin is associated with decreased lumbar radiculopathy pain
Lumbar radiculopathy pain represents a major public health problem, with few effective long-term treatments. Preclinical neuropathic and postsurgical pain studies implicate the kinase adenosine monophosphate activated kinase (AMPK) as a potential pharmacological target for the treatment of chronic pain conditions. Metformin, which acts via AMPK, is a safe and clinically available drug used in t...
متن کاملEvaluation of the efficacy of pregabalin on the treatment of patients with lumbosacral radiculopathy referring to Shahid Mofattah Yasuj Special Clinic
Background: Radiculopathy is defined as nerve root involvement and pressured that causes spinal pain. The problems of the lumbar and cervical disk herniation and diffusion pains are the most common problems in society so that 85% of people take low back pain at least once their life. These problems can be caused by herniated disc or spinal canal stenosis in the lumbar and cervical regions. The...
متن کاملSerum Levels of the Inflammatory Cytokines in Patients with Lumbar Radicular Pain Due to Disc Herniation
STUDY DESIGN Cohort study. PURPOSE This study primarily aimed to evaluate the serum levels of tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-4 in patients with lumbar radiculopathy 1 and 12 months after microdiscectomy. OVERVIEW OF LITERATURE Lumbar radiculopathy is possibly caused by inflammatory changes in the nerve root. The intraneural application of pro-inflammatory cytokines...
متن کاملProspective medium-term results of multimodal pain management in patients with lumbar radiculopathy
Lumbar radiculopathy is one of the most common diseases of modern civilisation. Multimodal pain management (MPM) represents a central approach to avoiding surgery. Only few medium-term results have been published in the literature so far. This study compared subjective and objective as well as anamnestic and clinical parameters of 60 patients who had undergone inpatient MPM because of lumbar ra...
متن کاملPostpartum Sacral Stress Fracture Mimicking Lumbar Radiculopathy in a Patient With Pregnancy-Associated Osteoporosis
Postpartum sacral fracture is relatively rare, and its diagnosis is often delayed. We herein report such a case of a 28-year-old patient who presented with an insidious-onset lower back pain, left buttock pain, and radicular symptoms mimicking lumbar radiculopathy. Laboratory tests showed a decreased 25-hydroxy vitamin D level, and the bone mineral densitometry of both femurs was below the expe...
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عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2014